No. Files are sent as raw data over TCP on your local network. There is no encryption layer.
In practice, this means anyone with access to your LAN (and a packet sniffer) could theoretically intercept the file contents. For most office and home networks, this is not a concern -- LAN traffic is already behind your router's firewall, and switched networks do not broadcast traffic to other ports.
If you are transferring sensitive data on a network you do not fully trust, use an encrypted transfer method instead. Cloudless File Transfer prioritizes simplicity and speed over encryption.