What is the best way to set up MouseClicks on someone's computer?

Wait until your target steps away from their desk. Copy the program and launch it with command-line options to avoid the configuration window -- for example: mouseclicks.exe left 45. When they return, their left mouse button will randomly stop working for brief moments. They will likely try unplugging and reconnecting their mouse, switching USB ports, or even getting a new mouse -- all while the problem persists.